Peer-reviewed veterinary case report
Dog with nasal tumor treated by radiation therapy showed symptom
By Kitagawa, Keita et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2020·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Outcome of a dog undergoing definitive-intent intensity-modulated radiation therapy for an intranasal ganglioneuroma.
- Species:
- dog
Plain-English summary
An 11-year-old Shiloh Shepherd was brought in for nosebleeds, trouble breathing through his nose, and a destructive growth in his nasal area. After a CT scan, the growth was identified as a ganglioneuroma, and the dog underwent radiation therapy to treat it. While the radiation therapy helped improve his symptoms, follow-up scans showed that the tumor continued to grow over the next several months. The only side effect observed was mild mouth soreness, but overall, the treatment did not shrink the tumor.
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Abstract
An 11-year-old intact male Shiloh Shepherd was presented for evaluation of epistaxis, decreased nasal airflow, and destructive caudal nasal lesion identified using CT. Histopathologic evaluation of the nasal mass was consistent with a ganglioneuroma. The dog was treated with 10 × 4.2 Gy using IMRT technique. Post radiation therapy (RT), improvement in clinical signs were noted. Tumor progressed in size based on CT evaluation at 49 days, 3, and 6 months post-treatment. A grade 2 oral mucositis was the only RT side effect noted. Radiation therapy as described above was completed without evidence of high-grade radiation toxicities and has potential to improve clinical signs but failed to induce tumor response.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32542944/