Peer-reviewed veterinary case report
Long-term results of radiotherapy with or without nasal surgery
By Adams, William M et al.·Published in Journal of the American Veterinary Medical Association·2005·Department of Surgical Sciences, United States·View original on PubMed →
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Original publication title: Outcome of accelerated radiotherapy alone or accelerated radiotherapy followed by exenteration of the nasal cavity in dogs with intranasal neoplasia: 53 cases (1990-2002).
- Species:
- dog
Plain-English summary
A group of 53 dogs with cancer in the nasal cavity received either radiotherapy alone or radiotherapy followed by surgery to remove the nasal cavity (exenteration). The dogs that had both treatments lived longer, with a median survival time of about 477 months, compared to just under 20 months for those who only had radiotherapy. However, the surgery group faced more complications, such as bleeding and infections. Overall, while surgery after radiotherapy can improve survival, it also comes with increased risks of chronic issues.
People also search for: dog nasal cancer treatment · dog radiotherapy side effects · exenteration surgery for dogs
Abstract
OBJECTIVE: To compare long-term results of radiotherapy alone versus radiotherapy followed by exenteration of the nasal cavity in dogs with malignant intranasal neoplasia. DESIGN: Retrospective study. ANIMALS: 53 dogs with malignant intranasal neoplasia. PROCEDURE: All dogs underwent radiotherapy consisting of administration of 10 fractions of 4.2 Gy each on consecutive weekdays. For dogs in the surgery group (n=13), follow-up computed tomography was performed, and dogs were scheduled for surgery if persistent or recurrent tumor was seen. RESULTS: Perioperative complications for dogs that underwent surgery included hemorrhage requiring transfusion (2 dogs) and subcutaneous emphysema (8). Rhinitis and osteomyelitis-osteonecrosis occurred significantly more frequently in dogs in the radiotherapy and surgery group (9 and 4 dogs, respectively) than in dogs in the radiotherapy-only group (4 and 3 dogs, respectively). Two- and 3-year survival rates were 44% and 24%, respectively, for dogs in the radiotherapy group and 69% and 58%, respectively, for dogs in the surgery group. Overall median survival time for dogs in the radiotherapy and surgery group (477 months) was significantly longer than time for dogs in the radiotherapy-only group (19.7 months). CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that exenteration of the nasal cavity significantly prolongs survival time in dogs with intranasal neoplasia that have undergone radiotherapy. Exenteration after radiotherapy may increase the risk of chronic complications.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16190593/