Peer-reviewed veterinary case report
Medical treatment results for corneal ulcers in dogs
By Guyonnet, A et al.·Published in The Journal of small animal practice·2020·Unité, France·View original on PubMed →
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Original publication title: Outcome of medical therapy for keratomalacia in dogs.
- Species:
- dog
Plain-English summary
A group of 53 dogs with corneal ulcers and keratomalacia (a severe eye condition) received intensive medical treatment using a combination of tobramycin eye drops and equine serum. Out of 57 ulcers treated, 31 healed successfully within about 5 days. Most dogs had good vision 60 days after treatment, but one dog developed a serious complication that required surgery a month later. Overall, the medical therapy worked well for many dogs, reducing the need for surgery.
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Abstract
OBJECTIVES: To evaluate the clinical and visual outcomes following intensive medical therapy for keratomalacia in dogs. MATERIALS AND METHODS: Medical records were screened to identify dogs with corneal ulcers and keratomalacia. All patients were given the same topical treatment protocol with frequent administrations of tobramycin in combination with equine serum. Surgical treatment during the first 15 days of follow-up was considered as medical treatment failure. RESULTS: We report on 57 ulcers with keratomalacia from 53 dogs. Medical treatment was successful in 31 of 57 ulcers with a median healing time of 5 days (range 2 to 15 days). At 60 days after epithelialisation, 14/15 medically-treated eyes were visual. In one case, corneal perforation was observed 1 month after healing and required surgical stabilisation. CLINICAL SIGNIFICANCE: Intensive medical therapy has the potential to achieve healing of some ulcers with keratomalacia. Surgical stabilisation in response to progression of stromal loss was required in less than half of the cases.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32065393/