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Peer-reviewed veterinary case report

Outcomes and signs of surgically removed salivary gland cancer in dogs

By Bush, Kaleigh M. et al.·Published in Veterinary Surgery·2023·Auburn University Auburn Alabama USA, United States·View original on Crossref

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Original publication title: Outcomes and clinical features associated with surgically excised canine salivary gland carcinoma: Amulti‐institutional, retrospective, Veterinary Society of Surgical Oncology study

Species:
dog

Plain-English summary

A group of 72 dogs with salivary gland cancer underwent surgery to remove the affected glands. The study found that the average survival time after surgery was about 5 years, which is better than what was previously thought. However, about 42% of the dogs experienced a return of the cancer, and 32% developed cancer in their lymph nodes. Dogs with lymph node involvement at the time of surgery had a shorter survival time. Overall, surgery is a viable option for dogs with this type of cancer, and it can lead to a good outcome.

People also search for: dog salivary gland cancer treatment · canine cancer surgery recovery · what to expect after dog surgery for cancer

Abstract

AbstractObjectiveThe objective of this study was to describe the clinical features, prognostic factors, and outcomes in dogs with surgically treated salivary gland carcinoma.Study designMulti‐institutional retrospective case series.AnimalsSeventy‐two client‐owned dogs from 16 institutions with surgically excised salivary gland carcinoma.MethodsMedical records of dogs undergoing sialoadenectomy from January 1, 2000 to January 1, 2020 were reviewed for signalment, clinical signs, preoperative staging results, preoperative mass evaluation, complications, histopathologic diagnosis, local recurrence, metastatic disease, and survival times. Survival functions were estimated using the Kaplan‐Meier estimator. Factors related to survival were individually tested using the log‐rank test.ResultsThe overall median survival time (MST) associated with salivary carcinoma was 1886 days. Local recurrence occurred in 29/69 (42%) dogs with an overall disease‐free interval (DFI) of 191 days. Metastatic disease occurred in 22/69 (31.9%) dogs, with an overall DFI of 299 days. Lymph node metastasis was present at the time of surgery in 11/38 (28.9%) dogs in which lymphadenectomy was performed at the time of surgery; these dogs had a shorter DFI at 98 days (P = .03) and MST at 248 days (P < .001).ConclusionThe prognosis for dogs with salivary gland carcinoma treated surgically was more favorable than previously reported. Nodal metastasis was a negative prognostic factor for canine salivary gland carcinoma.Clinical significanceSurgical intervention should be considered for dogs with salivary carcinoma.

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Original publication on Crossref: https://doi.org/10.1111/vsu.13928