Peer-reviewed veterinary case report
Outcomes and signs of salivary gland cancer in dogs after surgery
By Bush, Kaleigh M et al.·Published in Veterinary surgery : VS·2023·Auburn University, United States·View original on PubMed →
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Original publication title: Outcomes and clinical features associated with surgically excised canine salivary gland carcinoma: A multi-institutional, retrospective, Veterinary Society of Surgical Oncology study.
- Species:
- dog
Plain-English summary
A group of 72 dogs with salivary gland cancer underwent surgery to remove the affected tissue. The study found that the average survival time after surgery was about 5 years, although some dogs experienced a return of the cancer or spread to other areas. Dogs that had cancer spread to their lymph nodes at the time of surgery had a shorter survival time and a higher chance of the cancer coming back. Overall, surgical treatment showed promising results, suggesting that surgery can be a good option for dogs with this type of cancer.
People also search for: dog salivary gland cancer treatment · canine cancer surgery outcomes · dog lymph node metastasis prognosis
Abstract
OBJECTIVE: The objective of this study was to describe the clinical features, prognostic factors, and outcomes in dogs with surgically treated salivary gland carcinoma. STUDY DESIGN: Multi-institutional retrospective case series. ANIMALS: Seventy-two client-owned dogs from 16 institutions with surgically excised salivary gland carcinoma. METHODS: Medical records of dogs undergoing sialoadenectomy from January 1, 2000 to January 1, 2020 were reviewed for signalment, clinical signs, preoperative staging results, preoperative mass evaluation, complications, histopathologic diagnosis, local recurrence, metastatic disease, and survival times. Survival functions were estimated using the Kaplan-Meier estimator. Factors related to survival were individually tested using the log-rank test. RESULTS: The overall median survival time (MST) associated with salivary carcinoma was 1886 days. Local recurrence occurred in 29/69 (42%) dogs with an overall disease-free interval (DFI) of 191 days. Metastatic disease occurred in 22/69 (31.9%) dogs, with an overall DFI of 299 days. Lymph node metastasis was present at the time of surgery in 11/38 (28.9%) dogs in which lymphadenectomy was performed at the time of surgery; these dogs had a shorter DFI at 98 days (P = .03) and MST at 248 days (P < .001). CONCLUSION: The prognosis for dogs with salivary gland carcinoma treated surgically was more favorable than previously reported. Nodal metastasis was a negative prognostic factor for canine salivary gland carcinoma. CLINICAL SIGNIFICANCE: Surgical intervention should be considered for dogs with salivary carcinoma.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36647241/