Peer-reviewed veterinary case report
Survival and outcomes for dogs with grade 3 mast cell tumors
By Hume, Carrie Tupper et al.·Published in Journal of the American Animal Hospital Association·2011·Matthew J. Ryan Veterinary Hospital, United States·View original on PubMed →
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Original publication title: Outcomes of dogs with grade 3 mast cell tumors: 43 cases (1997-2007).
- Species:
- dog
Plain-English summary
A group of dogs with grade 3 mast cell tumors (a type of skin cancer) was studied to understand their outcomes. The average time before the cancer progressed was about 133 days, and the overall survival time was around 257 days. Factors like tumor size and whether the cancer had spread to lymph nodes were important in determining how long the dogs lived after treatment. The findings suggest that controlling the tumor locally and addressing lymph node involvement can lead to better outcomes for dogs with this type of cancer.
People also search for: dog mast cell tumor treatment · grade 3 mast cell tumor prognosis · dog skin cancer survival rate
Abstract
This study reports the outcomes of dogs with grade 3 mast cell tumors (MCTs). Clinical and histopathological data were available for 43 dogs. Median progression-free survival (PFS) and overall survival (OS) were 133 and 257 days, respectively. Tumor size, lymph node (LN) status, and mitotic index (MI) significantly influenced PFS in univariate analysis. Tumor size and LN status remained significant in the multivariate analysis. Lymph node status, local tumor control, LN treatment, and MI significantly influenced OS in univariate analysis but only LN status remained significant in multivariate analysis. These results confirm that locoregional control improves outcomes in patients with grade 3 MCTs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21164163/