Peer-reviewed veterinary case report
Overcoming Depression by Inhibition of Neural Burst Firing.
- Journal:
- Neuron
- Year:
- 2018
- Authors:
- Kim, Daesoo et al.
- Affiliation:
- Department of Biological Sciences · South Korea
Abstract
The N-methyl-D-aspartate receptor (NMDAR) antagonist ketamine has been found to have rapid and long-lasting antidepressive effects. Two elegant studies from Hailan Hu's laboratory (Cui et al., 2018; Yang et al., 2018) showed that ketamine blocks burst firing of neurons in the lateral habenula (LHb), rapidly relieving symptoms of depression.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/29879390/