Peer-reviewed veterinary case report
Overview of Transgenic Glioblastoma and Oligoastrocytoma CNS Models and Their Utility in Drug Discovery.
- Journal:
- Current protocols in pharmacology
- Year:
- 2016
- Authors:
- Chen, Fuyi et al.
- Affiliation:
- Department of Physiology and Neurobiology
Abstract
Many animal models have been developed to investigate the sources of central nervous system (CNS) tumor heterogeneity. Reviewed in this unit is a recently developed CNS tumor model using the piggyBac transposon system delivered by in utero electroporation, in which sources of tumor heterogeneity can be conveniently studied. Their applications for studying CNS tumors and drug discovery are also reviewed. © 2016 by John Wiley & Sons, Inc.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/26995546/