Peer-reviewed veterinary case report
Dog with repeated blood cell breakdown from fragrance products
By Lee, Sully et al.·Published in Journal of veterinary science·2024·Department of Veterinary Clinical Science, South Korea·View original on PubMed →
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Original publication title: Oxidative hemolytic crises in a dog due to fragrance products: clinical insights and treatment approaches.
- Species:
- dog
Plain-English summary
A 4-year-old female Pomeranian was brought to the vet with a brown tongue, dark urine, swelling, and vomiting. Tests showed she had a serious condition called oxidative hemolytic anemia, which was caused by exposure to certain fragrance products in her home. Despite treatments like antioxidants, methylene blue, hyperbaric oxygen therapy, and blood transfusions, her symptoms kept coming back. Once her owner removed all fragrance products and home remedies, the dog stopped having these dangerous crises and her health improved significantly.
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Abstract
IMPORTANCE: This is the first reported case of fragrance products-induced recurrent oxidative hemolytic anemia in a dog, detailing the successful therapeutic approach employed. CASE PRESENTATION: A 4-year-old intact female Pomeranian dog presented with brown tongue, pigmenturia, peripheral edema, and vomiting. Blood smears revealed a high count of eccentrocytes and Heinz bodies, along with a precipitous decline in packed cell volume and an increase in blood methemoglobin levels, suggesting an oxidative hemolytic crisis. This clinicopathological pattern recurred several times after the patient returned home. Antioxidants, methylene blue, hyperbaric oxygen (HBO) therapy, and blood transfusion were successfully employed to address recurrent hemolytic anemia; however, oxidative hemolytic crises recurred. After the owner removed exposure to various home remedies and fragrances, the clinical signs and hemolytic crises did not recur. CONCLUSIONS AND RELEVANCE: Recurring oxidative hemolytic crises should raise suspicions of environmental toxicity, which, although harmless in small quantities to humans, can be devastating to small-breed dogs. In addition to removing the causative agents, methylene blue and other antioxidants, along with HBO, may be beneficial in the acute management of oxidative hemolytic anemia.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39231789/