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Peer-reviewed veterinary case report

Dog with pancreatic lymphangioma and intestinal lymphangiectasia

By Ishikawa, Taisuke et al.·Published in Journal of veterinary internal medicine·2026·Veterinary Teaching Hospital, Japan·View original on PubMed

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Original publication title: Pancreatic lymphangioma and concurrent intestinal lymphangiectasia in a dog.

Species:
dog

Plain-English summary

A 2-year-old Border Collie was brought in for watery diarrhea and weight loss. Tests showed low protein levels and imaging revealed a cyst near the pancreas along with signs of intestinal swelling. The dog initially improved with an anti-inflammatory medication, but symptoms returned. After surgery to remove the cyst and take biopsies, the dog was diagnosed with pancreatic lymphangioma (a type of cyst) and intestinal lymphangiectasia (swelling of lymph vessels). Following surgery, the dog was treated with a lower dose of prednisolone and a low-fat diet, and it stayed healthy and symptom-free for a year.

People also search for: dog diarrhea weight loss treatment · Border Collie pancreatic cyst · low-fat diet for dog lymphangiectasia

Abstract

A 2-year-old Border Collie presented with watery diarrhea and weight loss. Laboratory testing disclosed hypoproteinemia and abdominal imaging identified striations suggestive of intestinal lymphangiectasia and a polycystic mass contiguous with the pancreas. Clinical signs were transiently ameliorated by using prednisolone at an anti-inflammatory dosage, but hypoproteinemia recurred accompanied by ascites within 1 month. Exploratory laparotomy identified pancreatic cysts and extensive inflammation of the duodenum and jejunum, and biopsy samples were taken for histopathology. The pancreatic cyst was lined by lymphatic vessels with no atypia and surrounding collagen fibers, highly suggestive of pancreatic lymphangioma. Histopathology of jejunal biopsy samples disclosed lipogranulomatous lymphangitis and lymphangiectasia. After the laparotomy, the dog was treated with prednisolone at a physiologic dosage and a low-fat diet, and remained asymptomatic for 1 year.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41742573/