Peer-reviewed veterinary case report
Dog with pancreatitis, skin nodules, and joint pain
By Hagelskamp, Abby et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2024·College of Veterinary Medicine, United States·View original on PubMed →
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Original publication title: Pancreatitis, panniculitis, and polyarthritis syndrome in a dog with hyalinizing pancreatic adenocarcinoma.
- Species:
- dog
Plain-English summary
A 10-year-old spayed female Cavalier King Charles Spaniel was brought to the vet with recurring abscesses on her back legs, fever, tiredness, and unexplained limping. After thorough testing, she was diagnosed with a rare condition linked to her chronic pancreatitis, which involved skin lesions and joint pain. Initially, treatment with immunosuppressive medication helped, but her symptoms returned after about a year, leading to her being euthanized. A postmortem exam revealed she had a type of pancreatic cancer along with the other issues.
People also search for: Cavalier King Charles Spaniel abscesses · dog pancreatitis treatment · dog limping and fever · dog skin lesions and joint pain · dog cancer symptoms.
Abstract
A 10-y-old spayed female Cavalier King Charles Spaniel dog was presented to the Veterinary Teaching Hospital because of recurrent chronic abscesses on the distal pelvic limbs, fever, lethargy, lameness of unknown etiology, and chronic pancreatitis. Sterile nodular panniculitis was diagnosed after an extensive workup, and the dog initially responded to immunosuppressive therapy, but relapse and spread of cutaneous lesions and acute lameness occurred after 11 mo, and euthanasia was elected. Postmortem examination confirmed hyalinizing pancreatic adenocarcinoma with pancreatitis, panniculitis, polyarthritis (PPP), and osteomyelitis. Histopathology and bacterial and fungal cultures were supportive of a sterile process, specifically the PPP syndrome, which is a rare, potentially life-threatening, systemic manifestation of pancreatic disease in both people and animals. To our knowledge, a clinicopathologic description of a hyalinizing pancreatic adenocarcinoma associated with this rare syndrome has not been reported previously in a dog.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/39233384/