Peer-reviewed veterinary case report
Papillomavirus-like Particles in Equine Medicine.
- Journal:
- Viruses
- Year:
- 2023
- Authors:
- Hainisch, Edmund K et al.
- Affiliation:
- Department for Companion Animals and Horses
- Species:
- horse
Abstract
Papillomaviruses (PVs) are a family of small DNA tumor viruses that can induce benign lesions or cancer in vertebrates. The observation that animal PV capsid-proteins spontaneously self-assemble to empty, highly immunogenic virus-like particles (VLPs) has led to the establishment of vaccines that efficiently protect humans from specific PV infections and associated diseases. We provide an overview of PV-induced tumors in horses and other equids, discuss possible routes of PV transmission in equid species, and present recent developments aiming at introducing the PV VLP-based vaccine technology into equine medicine.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/36851559/