Papular eosinophilic/mastocytic dermatitis (feline urticaria pigmentosa) in Devon Rex cats: A distinct disease entity or a histopathological reaction pattern?

Abstract

A maculopapular eruption with clinical and histological features similar to those previously described in Sphinx cats under the name of urticaria pigmentosa is reported in five unrelated Devon Rex cats. Physical examination revealed erythematous, occasionally crusted papules, with a bilaterally symmetrical linear distribution on the latero-ventral trunk in two cases and a diffuse distribution on the ventral thorax in the other three cats. One cat also had a greasy seborrhoea on the head and dorsum. Pruritus and pigmented macules were present only in cats affected by secondary bacterial infection. Histological examination of papules in all cats and of the lesional skin of the cat affected by greasy seborrhoea revealed the presence of a perivascular to diffuse mastocytic and eosinophilic infiltrate in the dermis. The mean numbers of nondegranulated and degranulated mast cells per mm(2) were 303.2 and 451.6, respectively. The condition waxed and waned in all cats, and exacerbations were controlled with prednisolone or essential fatty acids.