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Peer-reviewed veterinary case report

Paraneoplastic hypercalcemia in a dog with thyroid carcinoma.

Journal:
The Canadian veterinary journal = La revue veterinaire canadienne
Year:
2012
Authors:
Lane, Amy E & Wyatt, Kenneth M
Affiliation:
Perth Veterinary Oncology · United States
Species:
dog

Plain-English summary

This case involves a dog that had thyroid cancer and developed a condition called paraneoplastic hypercalcemia, which means the cancer caused high calcium levels in the blood. After surgery to remove the thyroid, the dog had low calcium levels and needed extra calcium and a medication called calcitriol to help. Over the next two years, when the vets tried to lower the extra calcium, the dog again had low calcium levels. Unfortunately, the dog later died from kidney failure, and there were no signs of thyroid cancer at that time.

Abstract

This case report describes a dog with thyroid carcinoma and paraneoplastic hypercalcemia. Following thyroidectomy the dog became hypocalcemic and required supplementation with calcitriol and calcium carbonate. During the following 2 years, attempts to reduce the supplementation resulted in hypocalcemia. The dog died from renal failure with no evidence of thyroid carcinoma.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/23543930/