Peer-reviewed veterinary case report
Dog with thymoma and high T cell count that cleared after surgery
By Batlivala, T P et al.·Published in The Journal of small animal practice·2010·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Paraneoplastic T cell lymphocytosis associated with a thymoma in a dog.
- Species:
- dog
Plain-English summary
A 4-year-old male neutered Australian shepherd was diagnosed with a thymoma, a type of tumor in the thymus gland, and had an unusual increase in certain white blood cells called T cells. The dog showed signs of this condition, but after surgery to remove the thymoma, the elevated T cell levels returned to normal within just 24 hours. This case highlights that thymomas can sometimes cause increased lymphocyte levels, which is not very common. The dog recovered well after the surgery.
People also search for: dog thymoma symptoms · Australian shepherd lymphocytosis treatment · dog surgery for thymoma
Abstract
A four-year-old male neutered Australian shepherd dog was diagnosed with a thymoma and concurrent mature T cell lymphocytosis. The lymphocytosis consisted of a mixed population of T cells expressing either CD4 or CD8 or neither marker, and the result of polymerase chain reaction for antigen receptor rearrangement was negative. The peripheral lymphocytosis resolved within 24 hours following thoracotomy and thymectomy. Similar cases have been reported in man, but the aetiology of the increased circulating lymphocytes remains unclear. Although peripheral lymphocytosis is an uncommon paraneoplastic syndrome associated with thymomas, thymoma should be considered as a differential when the increased lymphocytes consist of a mixed population of T cells.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20659303/