Peer-reviewed veterinary case report
Parasite protein pirates host cytoskeletal modulator during invasion.
- Journal:
- Trends in parasitology
- Year:
- 2021
- Authors:
- McCowin, Sayo et al.
- Affiliation:
- Department of Medicine · United States
Abstract
Host cytoskeletal rearrangements are an essential yet poorly understood component of Cryptosporidium invasion. Guérin et al. demonstrate that actin rearrangements occur immediately during adherence and capture a unique mechanism of invasion using live-cell imaging. The authors identify a parasite-secreted effector, ROP1, recruited by a host protein, LMO7, involved in pathogenesis.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/34598896/