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Peer-reviewed veterinary case report

Cat with bone cancer causing high blood calcium fixed by leg

By Yuki, Masashi et al.·Published in Veterinary clinical pathology·2015·Yuki Animal Hospital, Japan·View original on PubMed

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Original publication title: Parathyroid hormone-related protein-induced hypercalcemia due to osteosarcoma in a cat.

Species:
cat
Movement & jointsCats

Plain-English summary

A 15-year-old male mixed-breed cat was brought to the vet because of a tumor on his right back leg. Blood tests showed high levels of calcium and other substances, which were linked to a type of bone cancer called osteosarcoma. The vet performed surgery to remove the leg, and afterward, the cat's blood levels returned to normal. This means the surgery was successful in treating the cancer and its related symptoms.

People also search for: cat leg tumor treatment · osteosarcoma in cats · high calcium levels in cats · cat surgery recovery after amputation

Abstract

A 15-year-old castrated male mixed-breed cat was presented with a history of sarcoma of the distal right hind limb. Biochemical analysis revealed increased concentrations of blood urea, creatinine, total calcium, ionized calcium, and parathyroid hormone-related protein (PTHrP). The mass was removed surgically by amputation of the hind limb. Osteosarcoma was diagnosed based on histopathologic examination. All abnormal serum analyte concentrations improved immediately after surgery, including azotemia, total calcium, ionized calcium, and PTHrP. The biochemical results were attributed to osteosarcoma causing PTHrP-induced hypercalcemia.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/25614921/