Peer-reviewed veterinary case report
Patch test reactions to Malassezia yeast in healthy and affected
By Bond, R et al.·Published in Medical mycology·2006·Department of Veterinary Clinical Sciences, United Kingdom·View original on PubMed →
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Original publication title: Patch test responses to Malassezia pachydermatis in healthy basset hounds and in basset hounds with Malassezia dermatitis.
Plain-English summary
A group of basset hounds, some healthy and some with a skin condition called Malassezia dermatitis (caused by a type of yeast), were tested to see how they reacted to the yeast's extracts. The tests showed that both healthy and affected basset hounds could have positive reactions, but the affected dogs reacted more often. This suggests that the skin issues in basset hounds may be linked to their immune response to this yeast. If your basset hound has skin problems, it might be worth discussing this type of testing with your vet.
People also search for: basset hound skin problems · Malassezia dermatitis treatment · dog yeast infection symptoms
Abstract
The effects of the patch test application of Malassezia pachydermatis extracts were evaluated in seven healthy basset hounds and in seven basset hounds with Malassezia dermatitis. Antigens (4 and 0.4 mg/ml) and saline controls were applied for 48 h using filter paper discs in Finn chambers. One healthy basset hound and five affected hounds showed positive patch test reactivity to the yeast antigens. Positive patch test reactions were characterized histologically by mild epidermal hyperplasia and mild to moderate perivascular, periadnexal and interstitial infiltrates of neutrophils and CD3+ lymphocytes. Immediate intradermal test reactivity to M. pachydermatis antigens was seen in one healthy and one affected hound, whereas delayed intradermal test reactivity was seen in six healthy hounds and five affected hounds. This study indicates that patch test reactivity to M. pachydermatis antigen may occur in healthy basset hounds, and in contrast to delayed intradermal test reactivity, is more frequent in basset hounds with Malassezia dermatitis.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16882608/