Peer-reviewed veterinary case report
Pathogenesis of paratuberculosis.
- Journal:
- The Veterinary clinics of North America. Food animal practice
- Year:
- 2011
- Authors:
- Sweeney, Raymond W
- Affiliation:
- Department of Clinical Studies-New Bolton Center · United States
Abstract
Paratuberculosis in ruminants is characterized by oral ingestion of Mycobacterium avium subsp. paratuberculosis (MAP), followed by a long incubation period during which time MAP is able to survive within the host’s macrophages. Initially the infection is held in check by the host’s cell-mediated immune response, but gradually the host loses control of the infection. The infection incites a granulomatous inflammatory response in intestinal tissue and mesenteric lymph nodes, resulting in protein-losing enteropathy, malabsorption, diarrhea, weight loss, and edema.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22023832/