Peer-reviewed veterinary case report
Pathogenesis of porcine reproductive and respiratory syndrome virus.
- Journal:
- Current opinion in virology
- Year:
- 2012
- Authors:
- Chand, Ranjni J et al.
- Affiliation:
- Department of Diagnostic Medicine and Pathobiology · United States
Abstract
Porcine reproductive and respiratory syndrome virus (PRRSV) is the most costly viral pathogen facing a modern pig industry. A unique feature of the virus is the ability to cause severe clinical disease and maintain a life-long subclinical infection. Persistence at the population level poses the biggest challenge for the successful control and elimination of the disease. A mechanistic basis for persistence includes the evasion of innate and adaptive immune responses. Recent advances include the study of how the non-structural proteins (nsp's) inhibit the induction of type 1 interferon genes.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22709514/