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Peer-reviewed veterinary case report

Pathogenic genotype of major piroplasm surface protein associated with anemia in Theileria orientalis infection in cattle.

Journal:
Acta veterinaria Scandinavica
Year:
2017
Authors:
Kim, Suhee et al.
Affiliation:
National Institute of Animal Science · South Korea

Abstract

Serious disease outbreaks in cattle caused by Theileria orientalis have emerged in the Asia-Pacific region. Genetic variables of the major piroplasm surface protein (MPSP) expressed on the surface of the piroplasm inside T. orientalis-infected erythrocytes are considered to be associated with variation in the pathogenicity of T. orientalis. Our study describes the clinically relevant MPSP types associated with anemia in Theileria-infected cattle. These results revealed that MPSP expression plays an important role in hematological alterations in Theileria-infected cattle, and that MPSP type 1 is strongly associated with bovine anemia, which can be a potential target for the prevention of bovine theileriosis.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/28750636/