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Peer-reviewed veterinary case report

Pathogenicity of 2 porcine deltacoronavirus strains in gnotobiotic pigs.

Journal:
Emerging infectious diseases
Year:
2015
Authors:
Jung, Kwonil et al.

Abstract

To verify whether porcine deltacoronavirus infection induces disease, we inoculated gnotobiotic pigs with 2 virus strains (OH-FD22 and OH-FD100) identified by 2 specific reverse transcription PCRs. At 21-120 h postinoculation, pigs exhibited severe diarrhea, vomiting, fecal shedding of virus, and severe atrophic enteritis. These findings confirm that these 2 strains are enteropathogenic in pigs.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/25811229/