Peer-reviewed veterinary case report
Canine distemper virus types and effects in dogs in Turkey
By Karapınar, Zeynep et al.·Published in Acta veterinaria Hungarica·2023·Faculty of Veterinary Medicine·View original on PubMed →
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Original publication title: Pathological and molecular investigation of canine distemper virus: Phylogenetic analysis of co-circulating genetic lineages in Türkiye.
- Species:
- dog
Plain-English summary
A group of dogs suspected to have canine distemper virus (CDV) were examined for symptoms like coughing, vomiting, and neurological issues. Tests revealed severe lung and stomach infections, along with inflammation in the brain and other organs. The virus was found in various tissues, indicating a widespread infection. Unfortunately, CDV can lead to serious health problems, and the outcome for these dogs can be severe. Treatment typically focuses on supportive care, but the prognosis can vary greatly depending on the severity of the disease.
People also search for: dog coughing distemper symptoms · canine distemper treatment · dog vomiting and neurological issues
Abstract
Canine distemper virus (CDV) is a highly contagious virus that infects a wide variety of animals of carnivore species and may cause manifestations from subclinical infection to fatal disease. In this study, dogs clinically suspected having distemper were examined by reverse transcriptase-polymerase chain reaction (RT-PCR), histopathology and immuno-histochemistry. By histopathological examination, characteristic intracytoplasmic and/or intranuclear inclusion bodies were observed in the lung, stomach, small intestine, liver, kidney, spleen and central nervous system. Interstitial and broncho-interstitial pneumonia, gastroenteritis and encephalitis were revealed. CDV antigens were detected in all tissues with characteristic histopathological findings. The antigens were more abundant in the bronchial and bronchiolar epithelium and in the syntitial cells. Phylogenetic analyses were performed using the PCR-amplified partial sequences of the genes encoding the viral heamagglutinin and fusion proteins. The phylogenetic trees showed that the newly determined sequences were diverse and clustered within different lineages of the European or the Arctic strains.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37314889/