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Peer-reviewed veterinary case report

Lung and heart damage in Newfoundland dogs with Angiostrongylus

By Bourque, Andrea C et al.·Published in Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc·2008·Department of Pathology and Microbiology, Canada·View original on PubMed

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Original publication title: Pathological findings in dogs naturally infected with Angiostrongylus vasorum in Newfoundland and Labrador, Canada.

Species:
dog

Plain-English summary

Six dogs in Newfoundland were found to have a lung infection caused by a parasite called Angiostrongylus vasorum. These dogs showed symptoms like coughing and difficulty breathing due to pneumonia, and one dog even developed severe heart problems. In some cases, the infection led to seizures caused by bleeding in the brain. Treatment involved removing hundreds of adult worms from the lungs, and the dogs received supportive care. The study highlights how this parasite can cause serious health issues in dogs, particularly affecting their lungs and heart.

People also search for: dog coughing pneumonia treatment · dog seizures causes · Angiostrongylus vasorum symptoms in dogs

Abstract

Fifty-six dogs from St. John's, Newfoundland, Canada, were evaluated for Angiostrongylus vasorum infection. Small numbers of nematodes were found within pulmonary arteries of 6 dogs. Larvae were identified in fecal samples in 2 of 6 dogs. All 6 dogs had multifocal granulomatous pneumonia and sometimes foci of chronic thrombosis, which varied from very mild to severe. One dog had extensive pulmonary lesions resulting in cor pulmonale. Right heart failure was characterized by right ventricular hypertrophy, hepatic congestion, ascites, and hydrothorax. Microscopically, in most cases, eggs, larvae, and sometimes intravascular adults, were present within lung tissue sections. Small foci of granulomatous inflammation with and without larvae were present in kidney and brain in 4 dogs. An additional dog, diagnosed antemortem with angiostrongylosis via fecal examination, was also examined. Pathological findings consisted of severe pyogranulomatous interstitial pneumonia with myriad eggs, larvae, and numerous intravascular pulmonary adult nematodes with extensive arterial thrombosis. Five hundred and seventy-two adult worms were removed from pulmonary arteries. Foci of granulomatous inflammation, often associated with larvae and/or eggs, were present in tracheobronchial lymph nodes, adrenal gland, brain, and kidneys. Severe seizuring noted antemortem was attributed to several large, discrete areas of acute hemorrhagic infarction within the cerebrum and cerebellum. Natural A. vasorum infection in domestic dogs in eastern Newfoundland causes lung pathology of variable severity, which in some cases, may progress to cor pulmonale and which may be associated with extrapulmonary lesions and clinical signs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/18182502/