Peer-reviewed veterinary case report
Corneal squamous cell cancer in a dog and tumor protein p63 test
By Abin, K.A. et al.·Published in Journal of Veterinary and Animal Sciences·2025·View original on Crossref →
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Original publication title: Pathology and evaluation of immunohistochemical expression of tumour protein 63 (p63) in corneal squamous cell carcinoma in a dog
- Species:
- dog
Plain-English summary
A 6-year-old male Rottweiler was brought in with an unusual growth on his eye, which turned out to be corneal squamous cell carcinoma, a type of skin cancer affecting the eye surface. The mass was examined under a microscope, revealing cancerous cells that had invaded the surrounding tissue. The findings highlighted the importance of considering this type of cancer when a pet has an ulcerated mass on or around their eyes. Treatment options typically include surgical removal of the tumor, and early detection is crucial for a better outcome.
People also search for: dog eye growth · Rottweiler corneal cancer treatment · dog ulcerated eye mass
Abstract
In the present study, an exophytic mass on the corneal surface in a six-year-old male Rottweiler is described. Histopathologically, neoplastic cells appeared round to polygonal with vesicular to hyperchromatic nuclei and scanty to moderate eosinophilic cytoplasm. There was infiltration of neoplastic cells into underlying stroma as well as the ulcerated fibrovascular tissue. Based on the histopathological findings, the tumor was identified as corneal squamous cell carcinoma. Immunohistochemical expression of tumour protein 63 (p63) was evaluated in the tumour and a strong expression was detected. Squamous cell carcinoma should always be a differential whenever an ulcerated mass is found in the ocular and adnexal surface1
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Search related cases →Original publication on Crossref: https://doi.org/10.51966/jvas.2025.56.1.196-199