Peer-reviewed veterinary case report
Pathomorphological analysis of the pancreaticoduodenal organs in experimental pancreonecrosis induced by trypsin injection.
- Journal:
- Bulletin of experimental biology and medicine
- Year:
- 2013
- Authors:
- Nepomnyashchikh, L M et al.
- Affiliation:
- Institute of Regional Pathology and Pathomorphology
Abstract
Acute experimental pancreatitis induced by injection of trypsin into the pancreatic tissue exhibited characteristics of fulminant hemorrhagic pancreonecrosis (intense exudation of interlobular stroma, massive plasmo- and hemorrhages, foci of acinar cell autolysis involving by the end of day 1 an appreciable portion of the organ with formation of fields of necrosis and hemorrhagic imbibition of the glandular parenchyma, virtually completely without demarcation cellular reaction). Marked microcirculatory disorders and degenerative and necrobiotic changes in the duodenal mucosa and liver reflected the polyorgan nature of the pathological process. This model of hemorrhagic pancreonecrosis corresponded to the most severe forms of this conditions observed clinically.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/24131002/