Peer-reviewed veterinary case report
Patient-Derived Xenograft Models for Ovarian Cancer.
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Year:
- 2024
- Authors:
- Tran, Trang Minh et al.
- Affiliation:
- Hudson Institute of Medical Research · Australia
Abstract
Patient-derived xenograft (PDX) models play a crucial role for in vivo research. They maintain the original molecular characteristics of the human tumor and provide a more accurate tumor microenvironment, which cannot be replicated by in vitro models. This chapter describes four different transplantation methods, namely, intra-bursal, intrarenal capsule, intraperitoneal, and subcutaneous, to develop PDX models for ovarian cancer research.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/38676803/