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Peer-reviewed veterinary case report

New lipase test helps diagnose pancreatitis in dogs

By Ishioka, Katsumi et al.·Published in The Journal of veterinary medical science·2011·Department of Veterinary Nursing, Japan·View original on PubMed

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Original publication title: Patient-side assay of lipase activity correlating with pancreatic lipase immunoreactivity in the dog.

Species:
dog

Plain-English summary

A group of dogs with suspected pancreatitis had their blood tested for lipase activity, which is an enzyme that can indicate pancreatic issues. Researchers found that a new test called the FUJI DRI-CHEM slide accurately identified dogs with pancreatitis by measuring lipase levels, showing a strong correlation with another common test. This means that vets can use this new test right in their clinic to quickly diagnose pancreatitis and start treatment sooner. The findings suggest that this test could be a valuable tool for pet owners and veterinarians alike.

People also search for: dog pancreatitis symptoms · dog lipase test · how to treat pancreatitis in dogs

Abstract

Pancreatitis is a common exocrine pancreatic disease in dogs, and the pancreatic lipase immunoreactivity (PLI) test is used for diagnosis. Enzyme catalytic assay is thought to have low specificity, but a lipase activity assay with increased specificity has been developed in human clinical chemistry. We measured serum lipase activity of 65 client-owned dogs using the newly developed FUJI DRI-CHEM slide and compared the results with their PLI concentrations. The results showed a good correlation (r = 0.91), and the normal and pancreatitis dogs identified based on the PLI values were correctly separated based on lipase activity. The present study suggests that FUJI DRI-CHEM lipase activity would be helpful for diagnosis of pacreatitis in dogs and, in particular, that it can be used as a patient-side assay and contributes to immediate treatment.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21705846/