Peer-reviewed veterinary case report
Dog skin nodules caused by Mycobacterium murphy in Brazil
By M.A.A. Pereira et al.·Published in Arquivo Brasileiro de Medicina Veterinária e Zootecnia·View original on DOAJ →
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Original publication title: PCR-based identification of Mycobacterium murphy causing Canine Leproid Granuloma Syndrome in Niterói, southeast Brazil - case report
- Species:
- dog
Plain-English summary
A dog in Brazil was diagnosed with Canine Leproid Granuloma Syndrome (CLGS), which is a skin infection that causes nodules. The diagnosis was confirmed through tests that examined the skin lesions and identified the bacteria responsible using a special technique called PCR. This case is significant because it highlights the need for veterinarians to consider CLGS when examining dogs with similar skin problems. The dog received appropriate treatment based on the diagnosis, which can help manage the symptoms and improve the dog's condition.
People also search for: dog skin lumps treatment · canine leprosy symptoms · how to treat dog skin infections
Abstract
ABSTRACT Canine Leproid Granuloma Syndrome (CLGS), also known as canine leprosy, is a cutaneous nodular infectious disease caused by Mycobacterium sp.. Despite being reported worldwide, it is still quite unknown and underdiagnosed. Diagnosis may be achieved by cytopathology or histopathology of skin lesions, but identification of the infectious agent is complex, since bacterial in vitro growth is not possible, relying upon molecular techniques such as PCR to confirm Mycobacterium DNA in the sample. We report a CLGS case in Niteroi, Rio de Janeiro state, Brazil, diagnosed by cytopathology and submitted to molecular identification of the agent. PCR amplification of hsp65 gene was performed and revealed 100% genetic homology to M. murphy strain. This is the first CLGS report with molecular identification in Rio de Janeiro state, and this finding should raise awareness about CLGS as a differential diagnosis among granulomatous skin diseases in this region.
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Search related cases →Original publication on DOAJ: https://doi.org/10.1590/1678-4162-10079