Peer-reviewed veterinary case report
Testing mavacoxib for elbow osteoarthritis lameness in dogs using
By López, Sergio et al.·Published in BMC veterinary research·2019·Departamento de Patologí, Spain·View original on PubMed →
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Original publication title: Pedobarography: a novel approach to test the efficacy of treatments for lameness; an experience with mavacoxib in dogs with elbow osteoarthritis.
- Species:
- dog
Plain-English summary
Eleven large-breed dogs with limping due to elbow osteoarthritis were treated with mavacoxib, a pain medication, for three months. Before treatment, the dogs showed clear differences in pressure between their lame and healthy legs, indicating significant lameness. After three months of treatment, these differences were greatly reduced, suggesting that the dogs were moving more comfortably and had improved function. This study highlights how effective mavacoxib can be for helping dogs with joint pain and lameness.
People also search for: dog limping treatment · elbow osteoarthritis in dogs · mavacoxib for dog pain relief
Abstract
BACKGROUND: Pedobarographic analyses detect pressure redistribution among limbs and within limbs in humans, equids and dogs. The main objective of this study was to assess the usefulness of a set of pedobarographic parameters for the detection of lameness, as well as for its suitability for assessing the effects of therapies against osteoarthritis in dogs. With this purpose, eleven large-breed lame dogs with unilateral osteoarthritis due to elbow dysplasia were evaluated using a pressure platform prior to (D0) and after 3 months (D90) of treatment with mavacoxib, a COX-2 selective NSAID. The obtained parameters were: pressure distribution between lame and sound limbs, as well as paw area, mean pressure, and peak pressure of both lame and sound limbs. RESULTS: The results showed statistical differences in all these parameters between lame and sound limbs at D0; however, at D90, differences were significantly decreased as result of the treatment, indicating a substantial functional recovery under the study design conditions. CONCLUSIONS: The provided data prove the suitability of this novel technique in canine models for the quantitative and objective assessment of lameness, but also for the evaluation of treatments for lameness caused by articular pain.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31186043/