Peer-reviewed veterinary case report
Pelger-Huët anomaly causing unusual white blood cells in a cat
By Deshuillers, Pierre et al.·Published in Veterinary Clinical Pathology·2014·Department of Comparative Pathobiology Purdue University College of Veterinary Medicine West Lafayette IN USA, United States·View original on Crossref →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Pelger–Huët Anomaly in a cat
- Species:
- cat
Plain-English summary
A 14-year-old spayed female Domestic Shorthair cat was brought in for treatment of hyperthyroidism and was found to have an unusual blood condition called Pelger–Huët anomaly. This condition was identified when tests showed that about half of her white blood cells had an abnormal shape, but she showed no signs of illness related to inflammation. After further testing, including negative results for common feline viruses, the diagnosis was confirmed. Fortunately, the cat did not have any related health issues and continued to receive treatment for her hyperthyroidism.
People also search for: cat hyperthyroidism treatment · Pelger-Huët anomaly in cats · abnormal blood cells in cats
Abstract
AbstractA 14‐year‐old, spayed female Domestic Shorthair cat was referred to the Purdue University Veterinary Teaching Hospital (PUVTH) for iodine 131 treatment of hyperthyroidism. Upon arrival, a biochemistry profile and a CBC were performed. Approximately 50% of the neutrophils and all the eosinophils observed were hyposegmented with a mature, condensed chromatin pattern. Nuclei had a band to “dumbbell” shape, and rarely a round shape, suggesting a Pelger–Huët anomaly or a pseudo Pelger–Huët. Based on both a negative FeLV and FIV tests, the absence of any clinical signs to support an inflammatory process, and the persistence of this granulocytic morphology 6 months after its previous admission to the PUVTH, a diagnosis of Pelger–Huët anomaly was established in this cat.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on Crossref: https://doi.org/10.1111/vcp.12176