Peer-reviewed veterinary case report
Sudden death in 9-year-old Pekingese linked to rare liver lesion
By Sapierzyński, R·Published in Polish journal of veterinary sciences·2007·Department of Clinical Sciences·View original on PubMed →
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Original publication title: Peliosis hepatis-like lesion in a pekingese dog. A case report.
- Species:
- dog
Plain-English summary
A 9-year-old female Pekingese suddenly died, and an autopsy was performed to find out why. The examination revealed a swollen liver with unusual blood-filled spaces and severe fluid buildup in the abdomen. The liver showed signs of a rare condition called peliosis hepatis, which involves abnormal blood-filled areas within the liver. Unfortunately, due to the severity of the liver damage and other complications, the cause of death was linked to these serious liver issues.
People also search for: Pekingese sudden death causes · dog liver disease symptoms · peliosis hepatis in dogs
Abstract
Peliosis hepatis (PH) is a rare condition characterized by dilatation of hepatic sinusoids and the presence of blood-filled spaces within the liver. The disease occurs mainly in subjects exposed to toxic substances or estrogens, and is often asymptomatic. A 9 year-old pekingese female dog was sent to Division of Pathology for autopsy because of sudden death of unclear cause. Autopsy revealed severe hydroperitoneum (1500 ml of transsudate), dilatation of heart ventricles, passive hyperemia of lungs, spleen and kidneys. The liver was enlarged, with slightly wrinkled surface, with many red spots, of different size and shape. Microscopic examination of the liver revealed the presence of areas with severe dilatation of hepatic sinusoids, and multiple cystic spaces filled with blood. Some of these spaces were lined with endothelium and other were not. Spaces were different in shape and size and were localized in the areas between dilated sinusoids. Based on the macroscopic and microscopic examination, the liver lesions were identified as severe hepatic sinusoidal dilatation with formation of peliosis hepatis-like structures.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17388024/