Peer-reviewed veterinary case report
Pemphigus foliaceus skin disease signs and treatment in 91 dogs
By Mueller, Ralf S et al.·Published in Journal of the American Animal Hospital Association·2006·Department of Clinical Sciences, United States·View original on PubMed →
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Original publication title: Pemphigus foliaceus in 91 dogs.
- Species:
- dog
Plain-English summary
A group of 91 dogs with a skin condition called pemphigus foliaceus were studied, showing symptoms like crusty skin, pustules, and hair loss. The affected areas were mostly on their bodies, ears, faces, and foot pads. Tests showed specific skin cells that indicated the disease. Treatment with a combination of medications, prednisolone and azathioprine, worked well, with over half of the dogs going into remission and many others showing significant improvement.
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Abstract
A retrospective study of 91 dogs with pemphigus foliaceus was performed. Clinical signs of the disease included crusts (n=79), pustules (n=36), and alopecia (n=33). Lesions were most common on the trunk (n=53), inner pinnae (n=46), face (n=37), and foot pads (n=32). Cytological evaluation revealed acantholytic keratinocytes in 37 of 48 dogs. Results of combination treatment with prednisolone and azathioprine were comparable to results with prednisolone therapy alone. More than half of the dogs achieved remission with appropriate therapy, and another 25% significantly improved.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16611930/