Peer-reviewed veterinary case report
Puppy develops pemphigus-like skin reaction after juvenile cellulitis
By Horvath, Christa et al.·Published in Veterinary dermatology·2007·Clinic of Internal Medicine and Infectious Diseases·View original on PubMed →
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Original publication title: Pemphigus foliaceus-like drug reaction in a 3-month-old crossbreed dog treated for juvenile cellulitis.
- Species:
- dog
Plain-English summary
A 3-month-old male crossbreed dog developed skin lesions two weeks after getting routine vaccinations. Initially, the vet thought it was juvenile cellulitis (a skin infection) and treated him with antibiotics and anti-inflammatory medications. However, new skin issues appeared that were linked to a drug reaction similar to pemphigus foliaceus, an autoimmune skin disease. After stopping the medication, the new lesions cleared up, but the original ones needed glucocorticoids (steroid medication) to heal completely. The puppy eventually recovered after these treatments.
People also search for: puppy skin lesions after vaccination · juvenile cellulitis treatment in dogs · pemphigus foliaceus drug reaction in dogs
Abstract
Two weeks after administration of routine vaccinations, a 3-month-old, male crossbreed dog developed cutaneous lesions that were clinically and histopathologically consistent with a diagnosis of juvenile cellulitis. The patient was treated with systemic antibacterial, antibacterial ophthalmic ointment and nonsteroidal anti-inflammatory drugs. Within 1 week, new skin lesions that were clinically, histopathologically and immunohistochemically consistent with pemphigus foliaceus developed. The latter completely resolved following drug withdrawal, suggesting a pemphigus foliaceus-like drug reaction. However, the initial lesions persisted and required glucocorticoid therapy to effect resolution. To the authors' knowledge, this is the first reported case of a puppy developing juvenile cellulitis followed by a pemphigus foliaceus-like reaction shortly thereafter, in response to drug therapy.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17845624/