Peer-reviewed veterinary case report
Dog with crusty skin lesions diagnosed with pemphigus foliaceus
By Shinya, K et al.·Published in The Journal of veterinary medical science·1996·Marupi Lifetech Co., Japan·View original on PubMed →
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Original publication title: Pemphigus foliaceus with typical histological and immunohistological findings in a dog.
- Species:
- dog
Plain-English summary
A 7-year-old female mongrel dog had stubborn skin lesions for about a year, mainly around her nose and eyes, which looked crusty and scaly. A skin biopsy revealed that the dog had pemphigus foliaceus, an autoimmune skin disease that causes pustules and skin irritation. The vet confirmed the diagnosis through specific tests that showed abnormal immune responses in the skin. While the abstract does not mention treatment details or outcomes, pemphigus foliaceus can often be managed with medications that suppress the immune system.
People also search for: dog skin lesions treatment · pemphigus foliaceus in dogs · crusty skin on dog nose · autoimmune skin disease in dogs
Abstract
A seven-year-old female mongrel dog showed incurable skin lesions for about a year. The lesions were at nasal bridge and periocular area, and were composed of crust formation and scaling. Biopsy specimens from the skin lesions possessed with multiple intraepidermal pustules containing many acatholytic keratinocytes. Direct immunoperoxidase stain using paraffin-embedded section showed IgG deposition at the intercellular area of upper epidermis and follicular infundibula. IgG was not detected at basement membrane zone. Clinical and pathological findings of the present case were identical to those of pemphigus foliaceus, an uncommon pustular autoimmune skin disease.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8877989/