Peer-reviewed veterinary case report
Immune skin disease causing feather loss in Korean black-bone fowl
By Han, Jae-Ik et al.·Published in Avian diseases·2008·Department of Veterinary Medicine, South Korea·View original on PubMed →
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Original publication title: Pemphigus-like immune-mediated dermatosis in a Korean native black-bone fowl.
Plain-English summary
A 3-year-old female Korean native black-bone fowl was brought in with severe skin problems, including thickened skin and feather loss on her head, neck, and shoulders. Previous antibiotic treatments didn’t help her condition. After testing, the vet diagnosed her with a pemphigus-like immune-mediated dermatosis, which is a type of autoimmune skin disease. Treatment with prednisolone, a steroid medication, successfully cleared up her skin lesions, and she started to regrow some feathers.
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Abstract
A 3-yr-old female Korean native black-bone fowl weighing 1 kg presented with refractory dermatosis characterized by hyperkeratosis and alopecia on the head, neck, and scapular region. Antibiotic therapy before referral had not reduced the severity of lesions. Histopathologic findings revealed hyperkeratosis, acantholysis, heterophil infiltration, and ballooning degeneration in the epidermis. Immunohistochemical analysis showed immunoglobulin G deposits in the intercellular spaces of the intermediate layer of the epidermis. Based on these observations, this case was diagnosed as a pemphigus-like immune-mediated dermatosis. The administration of prednisolone eliminated the lesions, and the feathers grew back partially.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/19166071/