Peer-reviewed veterinary case report
Dog with oral and skin ulcers treated for pemphigus vulgaris
By van den Berg, Johanna & Lange, Katrin·Published in Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere·2025·Anicura Deutschland GmbH·View original on PubMed →
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Original publication title: [Pemphigus vulgaris - a case report].
- Species:
- dog
Plain-English summary
A 9-year-old mixed-breed dog was brought in with painful sores and blisters in his mouth, around his eyes, and on his nose, tail, and paws. After thorough testing, the vet diagnosed him with pemphigus vulgaris, a rare autoimmune skin condition. The dog was treated with long-term immunosuppressive medications, including Prednisolone and Azathioprine, which helped him achieve complete remission. He is currently doing well and free of symptoms.
People also search for: dog mouth sores treatment · pemphigus vulgaris in dogs · dog skin problems treatment
Abstract
Pemphigus vulgaris (PV) represents a rare autoimmune dermatosis. The therapeutic agents of choice are immunosuppressants, which are used in form of a monotherapy or as a combination treatment depending on the clinical picture. This report provides a current literature review and describes a case of pemphigus vulgaris in a 9-year-old, male, castrated, medium-sized mixed-breed dog. The dog presented with characteristic cutaneous and mucosal lesions showing oral mucosal vesicles and ulcerations as well as ulcerations in the periocular region as well as on the planum nasale, tail base, and the paws. Based on the clinical signs and the results of the further and histological examinations, the diagnosis was confirmed. Using long-term immunosuppressive therapy (Prednisolone, Azathioprine) the dog attained complete remission up to the present time.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/41092914/