Peer-reviewed veterinary case report
Percutaneous doxycycline sclerotherapy in a horse with a mandibular aneurysmal bone cyst.
- Journal:
- Veterinary surgery : VS
- Year:
- 2022
- Authors:
- Perez, Jairo A et al.
- Affiliation:
- Department of Clinical Sciences · United States
- Species:
- horse
Plain-English summary
A one-year-old Standardbred filly was treated for a growing swelling in her jaw caused by a type of bone cyst called an aneurysmal bone cyst. The treatment involved injecting a foam made from doxycycline, an antibiotic, directly into the cyst three times over a few months. After the treatments, the size of the cyst significantly decreased, and the swelling in her jaw completely went away without any side effects from the injections. Overall, the treatment was successful in resolving the issue.
Abstract
OBJECTIVE: To describe the use and outcome of sclerotherapy with intralesional doxycycline foam in a horse with a mandibular aneurysmal bone cyst. STUDY DESIGN: Case report. ANIMALS: Client-owned 1 year old Standardbred filly. METHODS: The horse presented for progressive mandibular swelling. A 10 mg/mL doxycycline foam was prepared for intralesional injection. Three doses were injected into the lesion under computed tomographic guidance at 6 and 15 weeks after initial treatment. Volume reduction was monitored after each treatment with 3D volumetric rendering and region of interest segmentation using commercially available software. RESULTS: The volume of the lesion decreased from 458.7455 cmbefore treatment, to 363.3101 cmat 6 weeks, 273.5855 cmat 15 weeks, and 247.2316 cm6 months later, resulting in a total reduction of 54% of the initial volume. Bone formation was noted in the lesion. No adverse effects related to doxycycline foam injections were noted. The mandibular swelling was resolved after treatment. CONCLUSION: Intralesional doxycycline sclerotherapy was shown to be efficacious in reducing the volume of the aneurysmal bone cyst in the horse presented in this report. There was complete resolution of mandibular swelling with no side effects related to the intralesional injections.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/35730789/