Peer-reviewed veterinary case report
Horse with Cushing's syndrome treated with pergolide
By Muñoz, M C et al.·Published in The Veterinary record·1996·Departamento de Patologí, Spain·View original on PubMed →
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Original publication title: Pergolide treatment for Cushing's syndrome in a horse.
- Species:
- horse
Plain-English summary
A 16-year-old male Hanoverian horse had been losing weight, growing an unusual amount of hair, and drinking and urinating a lot for the past three months. Tests showed some issues with his white blood cells, blood sugar levels, and liver function, leading to a suspected diagnosis of Cushing's syndrome (a condition caused by too much cortisol). Further tests indicated he likely had a pituitary tumor. After starting treatment with pergolide, the horse showed positive changes in his health and blood tests within one to six months.
Abstract
A 16-year-old, male, Hanoverian horse had a three-month history of weight loss, hirsutism and polyuria/polydypsia. Examinations revealed neutrophilia, lymphopenia, hyper glycaemia and abnormalities in hepatic function. A tentative diagnosis of hyperadrenocorticism was made. The results of thyroid-releasing hormone and combined dexamethasone suppression and ACTH stimulation tests suggested the presence of a pituitary adenoma. The horse was treated with pergolide and beneficial clinical and biochemical responses were observed within one to six months.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8839490/