Peer-reviewed veterinary case report
Pergolide treatment for Cushing's syndrome in a horse.
- Journal:
- The Veterinary record
- Year:
- 1996
- Authors:
- Muñoz, M C et al.
- Affiliation:
- Departamento de Patologí · Spain
- Species:
- horse
Plain-English summary
A 16-year-old male Hanoverian horse had been losing weight, growing an unusual amount of hair, and drinking and urinating a lot for the past three months. Tests showed some issues with his white blood cells, blood sugar levels, and liver function, leading to a suspected diagnosis of Cushing's syndrome (a condition caused by too much cortisol). Further tests indicated he likely had a pituitary tumor. After starting treatment with pergolide, the horse showed positive changes in his health and blood tests within one to six months.
Abstract
A 16-year-old, male, Hanoverian horse had a three-month history of weight loss, hirsutism and polyuria/polydypsia. Examinations revealed neutrophilia, lymphopenia, hyper glycaemia and abnormalities in hepatic function. A tentative diagnosis of hyperadrenocorticism was made. The results of thyroid-releasing hormone and combined dexamethasone suppression and ACTH stimulation tests suggested the presence of a pituitary adenoma. The horse was treated with pergolide and beneficial clinical and biochemical responses were observed within one to six months.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/8839490/