Peer-reviewed veterinary case report
Periodontal treatment raises blood nitric oxide in dogs
By Nemec, A et al.·Published in Research in veterinary science·2013·William R. Pritchard Veterinary Medical Teaching Hospital, United States·View original on PubMed →
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Original publication title: Periodontal disease, periodontal treatment and systemic nitric oxide in dogs.
- Species:
- dog
Plain-English summary
A group of 32 dogs with periodontal disease (gum disease) received treatment to improve their dental health. After the treatment, blood tests showed that dogs with more severe gum disease had an increase in certain markers related to nitric oxide, which may indicate a response to the therapy. However, the results varied widely among individual dogs, and not all showed significant changes. Overall, the treatment seemed to help dogs with advanced periodontal disease, but the effects can differ from one dog to another.
People also search for: dog gum disease treatment · periodontal disease in dogs · dog dental health improvement
Abstract
Thirty-two client-owned dogs treated for periodontal disease were divided in group 1 if no periodontitis, group 2 if ≤25%, and group 3 if >25% of the teeth present were affected with periodontitis. Blood was tested before and 2 weeks after periodontal therapy for nitrosyl hemoglobin (HbNO), plasma nitrite/nitrate (NOx) and 3-nitrotyrosine (NT) levels. No HbNO was detected in any of the animals tested. There was no significant difference in the NOx plasma levels within each group or across the groups before and after the treatment, but a noticeable increase in NOx plasma levels was observed in group 3 after the treatment. Plasma NT was detected in only one third of the animals. NO levels varied greatly across individual dogs. The data are suggestive of an overall increase in systemic NO response 2 weeks after periodontal treatment in dogs with advanced periodontal disease, but the response is greatly individually-dependent.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23158853/