Peer-reviewed veterinary case report
Dog with sudden itchy skin swelling and high eosinophil blood cells
By Pace A & Hendricks J·Published in Veterinary Medicine: Research and Reports·2025·Emergency and Critical Care Service, GB
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Original publication title: Peripheral Eosinophilia in a Confirmed Case of Canine Acute Eosinophilic Dermatitis with Edema (Wells-Like Syndrome)
- Species:
- dog
Plain-English summary
A 1-year-old female spayed Terrier Mix was brought in for ongoing stomach issues and new skin problems, including swelling and irritation. Blood tests showed a high level of eosinophils, which are white blood cells often linked to allergic reactions or infections. Skin biopsies confirmed she had acute eosinophilic dermatitis with edema, a condition that can cause severe skin reactions. The dog was treated with corticosteroids for three weeks, and she made a full recovery.
People also search for: dog skin problems treatment · Terrier Mix with swelling · eosinophilic dermatitis in dogs · corticosteroids for dog skin issues
Abstract
Ashley Pace, Jeanette Hendricks Department of Emergency and Critical Care, Advanced Critical Care Emergency and Specialty Services, Los Angeles, Culver City, CA, USACorrespondence: Ashley Pace, Department of Emergency and Critical Care, Advanced Critical Care Emergency and Specialty Services, Los Angeles, 9599 Jefferson Blvd, Culver City, CA, 90232, USA, Email ashley.pace@thirvepet.comAbstract: This case report describes a peripheral eosinophilia in a dog diagnosed with canine acute eosinophilic dermatitis with edema (CAEDE). A 1-year-old female spayed Terrier Mix canine presented as a referral from their primary care veterinarian for gastrointestinal signs that were recently treated, but ongoing, and a new dermatopathy. Her leukogram revealed an eosinophilia, not previously present at the onset of her gastrointestinal signs, and skin biopsies were consistent with diagnosis of CAEDE. Although the definitive cause of the development of CAEDE in this patient is ultimately unknown, the patient made a full recovery following treatment with corticosteroids over a three-week treatment course. To the authors’ knowledge, this is the first report of a confirmed diagnosis of CAEDE to present with peripheral eosinophilia on complete blood count (IDEXX Procyte Dx).Keywords: CAEDE, WLS, gastroenteritis, dermatopathy, metronidazole, eosinophil
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