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Peer-reviewed veterinary case report

Long-lasting high vitamin D levels in dog after rodent poison exposure

By Gerhard, Charlotte & Jaffey, Jared A·Published in Frontiers in veterinary science·2019·Department of Small Animal Medicine and Surgery, United States·View original on PubMed

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Original publication title: Persistent Increase in Serum 25-Hydroxyvitamin D Concentration in a Dog Following Cholecalciferol Intoxication.

Species:
dog

Plain-English summary

A 4-year-old neutered Shih-Tzu mix was brought to the vet for intermittent vomiting, not eating, increased thirst, and frequent urination after being exposed to cholecalciferol, a type of rat poison. The vet monitored the dog's vitamin D levels over time and provided long-term treatment to manage the effects of the poisoning. This case highlights the importance of tracking vitamin D levels in dogs that have ingested cholecalciferol to ensure proper recovery. With appropriate care, the dog can recover from the toxicity.

People also search for: dog vomiting after rat poison · Shih-Tzu cholecalciferol poisoning treatment · increased thirst in dogs after poisoning

Abstract

Cholecalciferol is becoming an increasingly utilized rodenticide in the United States due to changes implemented by the Environmental Protection Agency (EPA) to reduce unintended exposure of wildlife to second-generation anticoagulant rodenticides. The lipophilic properties of cholecalciferol and prolonged tissue elimination are well-documented; however, long-term clinical ramifications are unknown. This report describes unique clinicopathologic and treatment features during the acute phase of cholecalciferol rodenticide toxicosis in a 4-year-old neutered Shih-Tzu mix that presented for intermittent vomiting, anorexia, polyuria, and polydipsia. In addition, this report also highlights the potential benefit of serial measurements of serum 25-hydroxyvitamin D concentrations and long-term treatment in the chronic phase of cholecalciferol rodenticide toxicosis in dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/31998760/