Peer-reviewed veterinary case report
Persistent high reticulocyte count in poodle macrocytosis case
By Boyd, Susan P. & Best, Matthew P.·Published in Veterinary Clinical Pathology·2018·QML Vetnostics Brisbane Qld Australia, Australia·View original on Crossref →
PetCaseFinder translated the abstract of this peer-reviewed paper into plain English so pet owners can read it. We do not publish original research — every detail traces back to the citation above. How we work →
Original publication title: Persistent reticulocytosis in a case of poodle macrocytosis
- Species:
- dog
Plain-English summary
A 14-year-old Miniature Poodle was found to have an unusual blood condition called macrocytosis, where red blood cells are larger than normal, along with a high number of immature red blood cells (reticulocytes). Despite these findings, the dog did not show signs of anemia or other blood issues. The vet noted specific changes in the dog's bone marrow that are linked to a genetic condition known as poodle macrocytosis. While the dog remained healthy overall, the persistent high levels of reticulocytes raised questions about a possible variation of this inherited condition.
People also search for: Miniature Poodle blood condition · poodle macrocytosis symptoms · dog reticulocytosis treatment
Abstract
AbstractA healthy 14‐year‐old, male neutered, Miniature Poodle was found to have a persistent erythrocyte macrocytosis and reticulocytosis with a normal and stableHCT. The hematologic features of macrocytosis, increased Howell‐Jolly bodies, and metarubricytosis, in the absence of anemia or other cytopenias, combined with the cytologic evidence of bone marrow erythroid dysplasia, including megaloblastosis, binuclearity, increased mitotic activity, and nuclear fragmentation, are consistent with previous reports of congenital dyserythropoiesis termed poodle macrocytosis. We speculate that the additional presence of persistent reticulocytosis in the absence of an identifiable stimulus for accelerated erythropoiesis may represent a phenotypic variation of this inherited condition, and the morphologic abnormalities of the dyserythropoiesis are described.
Find similar cases for your pet
PetCaseFinder finds other peer-reviewed reports of pets with the same symptoms, plus a plain-English summary of what was tried across them.
Search related cases →Original publication on Crossref: https://doi.org/10.1111/vcp.12626