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Peer-reviewed veterinary case report

Pet cancer cases and treatments at a Spanish vet hospital 2015-2024

By Romero, Beatriz et al.·Published in Frontiers in veterinary science·2025·Department of Biomedical Sciences, Spain·View original on PubMed

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Original publication title: Pet cancer cases and patterns of treatment at a Spanish veterinary teaching hospital: a retrospective study from 2015 to 2024.

Species:
dog

Plain-English summary

A study at a veterinary teaching hospital in Spain found that cancer is a leading cause of death in pets, particularly in older dogs. Out of 123 pets diagnosed with tumors, most were dogs, with many having malignant tumors in areas like the mammary glands or skin. Treatments included surgery for nearly half of the pets and chemotherapy for about a third, often using oral medications. Unfortunately, euthanasia was necessary for about 27% of the animals due to the severity of their conditions.

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Abstract

Cancer is one of the most common causes of death for companion animals. The study aimed to describe the characteristics of the clinical cases of pets attending at the Veterinary Teaching Hospital (University of Leon, Spain) and diagnosed with tumors. A retrospective study was carried out between 2015 and 2024. A total of 123 animals comprising 107 dogs and 16 cats were obtained from the clinical records. A mean annual incidence risk of 530 of 100,000 animals was calculated. Most animals were dogs (87.0%), females (62.6%), purebred (77.2%) and aged (78.9%). Tumors were mainly malignant (87.8%), they were of epithelial origin (40.7%), and mostly located in mammary glands (27.6%) or skin/mucosa (26.8%). Carcinoma (35.8%) and lymphoma (19.5%) were the major histological types. Almost half of the animals underwent surgical treatment (42.3%). Chemotherapy was administered to 37.4% of the animals, mostly by the oral route. QL01E (protein kinase inhibitors) was the main pharmacological group employed. Concomitant treatments and dietary supplements were also used. Euthanasia was applied to 26.8% of the animals.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/40697645/