Peer-reviewed veterinary case report
Phage T7 as a Potential Platform for Vaccine Development.
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Year:
- 2022
- Authors:
- Wong, Chuan Loo et al.
- Affiliation:
- Faculty of Biotechnology and Biomolecular Sciences
Abstract
Bacteriophages have been explored for their uses in vaccine development, due to the ease of propagation while displaying epitopes in high density. Bacteriophage T7 has been demonstrated to be useful in the production of potential vaccine candidates for various diseases, including influenza A, foot-and mouth disease (FMD), and cancers. In this chapter, we described the use of phage T7 to display potential foot-and-mouth disease virus (FMDV) epitope, from cloning to expression, purification, and immunization in a mouse model.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/34918242/