Peer-reviewed veterinary case report
Pharmacodynamics of doxycycline in a murine malaria model.
- Journal:
- Antimicrobial agents and chemotherapy
- Year:
- 2007
- Authors:
- Batty, Kevin T et al.
- Affiliation:
- School of Pharmacy · Australia
Abstract
Doxycycline is reported to impair second-generation parasite schizogony. The effects of doxycycline alone and combined with dihydroartemisinin were investigated in a murine malaria model. Doxycycline lowered the rate of parasite growth within 2 days, with maximum effect in 6 days. Addition of dihydroartemisinin led to an additive antimalarial effect.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/17876000/