Peer-reviewed veterinary case report
Enrofloxacin vs doxycycline for cat conjunctivitis from Chlamydophila
By Gerhardt, N et al.·Published in The Veterinary record·2006·Department of Small Animal Medicine, Germany·View original on PubMed →
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Original publication title: Pharmacokinetics of enrofloxacin and its efficacy in comparison with doxycycline in the treatment of Chlamydophila felis infection in cats with conjunctivitis.
- Species:
- cat
Plain-English summary
A group of 25 cats with conjunctivitis (eye inflammation) caused by Chlamydophila felis were treated with either enrofloxacin or doxycycline for 14 days. Both medications showed similar effectiveness in improving the cats' eye symptoms and reducing the infection, although some cats still tested positive for the infection after treatment. Fortunately, no side effects were noted in the cats receiving enrofloxacin. This suggests that both antibiotics can be effective options for treating this type of eye infection in cats.
People also search for: cat conjunctivitis treatment · Chlamydophila felis in cats · enrofloxacin for cat eye infection
Abstract
The concentrations of enrofloxacin were measured in the tears, saliva and serum of 14 cats with signs of upper respiratory tract infection and eight with no signs, after daily doses of 5 mg/kg. Enrofloxacin concentrations above the minimum inhibitory concentration of Chlamydophila felis were found in the saliva and tears of the cats with and without signs of upper respiratory tract infection. In a prospective randomised clinical trial, the efficacy of enrofloxacin against C. felis infection in cats with conjunctivitis was compared with the efficacy of doxycycline. Twenty-five cats were randomly assigned to treatment with either enrofloxacin or doxycycline for 14 days; 15 of the cats tested positive for C. felis by an immunofluorescent antibody test on conjunctival swabs. The two treatment groups showed equal improvements in the clinical signs of conjunctivitis and C. felis infection status; in each group three cats were still C. felis antigen-positive after the 14-day course of treatment, indicating a persistent infection. No side effects were observed in the cats treated with enrofloxacin.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17071671/