Peer-reviewed veterinary case report
Phenotypical Characteristics of Chemically Induced Mammary Tumor.
- Journal:
- Bulletin of experimental biology and medicine
- Year:
- 2017
- Authors:
- Kabakov, A V et al.
- Affiliation:
- Research Institute of Clinical and Experimental Lymphology
Abstract
The histological and immunohistochemical type of chemically induced (injection of N-methyl-N-nitrosourea into the mammary gland) breast tumor was studied in Wistar females. The tumor induced by N-methyl-N-nitrosourea was moderately differentiated adenocarcinoma with infiltrative growth lacking estrogen-α and human epidermal growth factor receptors, and expressing progesterone receptors; tumor cells were characterized by high proliferative activity. This variant of chemically induced breast tumor corresponds to human breast cancer luminal type B.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28853066/