Peer-reviewed veterinary case report
Dog with esophageal cancer treated by photodynamic therapy
By Jacobs, T M & Rosen, G MĀ·Published in Journal of the American Animal Hospital AssociationĀ·2000Ā·The Park Pet Hospital, United StatesĀ·View original on PubMed ā
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Original publication title: Photodynamic therapy as a treatment for esophageal squamous cell carcinoma in a dog.
- Species:
- dog
Plain-English summary
An 11-year-old male Labrador retriever was diagnosed with esophageal squamous cell carcinoma after showing signs of regurgitation and weight loss. The dog received photodynamic therapy, a treatment that uses light to help reduce tumor size, three times over two months. While the therapy led to some improvement, including a decrease in tumor size and the ability to eat again, the dog ultimately had to be euthanized nine months later due to complications from the cancer and pneumonia. This case highlights the challenges of treating this aggressive type of cancer in dogs.
People also search for: dog regurgitation treatment Ā· Labrador esophageal cancer Ā· photodynamic therapy for dogs
Abstract
Intrathoracic esophageal squamous cell carcinoma was diagnosed by endoscopy in an 11-year-old, castrated male Labrador retriever with signs of regurgitation and weight loss. Photodynamic therapy with photofrin was administered three times under endoscopic guidance over a two-month period. A partial response to photodynamic therapy was supported by a reduction in tumor size (noted on serial endoscopic examinations) and by a return to oral alimentation. The dog was euthanized due to recurrent regurgitation and aspiration pneumonia nine months after the onset of therapy. Necropsy revealed marked local invasiveness and regional lymph node metastasis of the esophageal squamous cell carcinoma in addition to pneumonia. The application of photodynamic therapy in the treatment of canine esophageal squamous cell carcinoma is discussed and compared with the human literature.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/10825099/