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Peer-reviewed veterinary case report

Phylogenetics and pathogenesis of early avian influenza viruses (H5N1), Nigeria.

Journal:
Emerging infectious diseases
Year:
2008
Authors:
Aiki-Raji, Comfort O et al.
Affiliation:
University of Ibadan
Species:
bird

Abstract

Three highly pathogenic avian influenza subtype H5N1 and 4 Newcastle disease viruses were isolated from sick or dead chickens in southwestern Nigeria. Sequencing and phylogenetic analysis placed them within H5N1 subclade 2.2.2. Intravenous and intranasal pathogenicity tests produced systemic disease with vascular endothelial cell tropism in chickens.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18976562/